SDCBP and KCNH1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SDCBP	KCNH1
Description		syndecan binding protein	potassium voltage-gated channel subfamily H member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Interleukin-5 Receptor Complex Adherens Junction Focal Adhesion Membrane Nuclear Membrane Azurophil Granule Lumen Melanosome Membrane Raft Synapse Extracellular Exosome Blood Microparticle Extracellular Vesicle	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Cell Junction Dendrite Axolemma Early Endosome Membrane Perikaryon Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Postsynaptic Density Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Frizzled Binding Interleukin-5 Receptor Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Cytoskeletal Adaptor Activity Identical Protein Binding Syndecan Binding Protein Heterodimerization Activity Protein N-terminus Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Protein Kinase Binding Cyclic Nucleotide Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding 14-3-3 Protein Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Negative Regulation Of Receptor Internalization Protein Targeting To Membrane Substrate-dependent Cell Migration, Cell Extension Chemical Synaptic Transmission Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Actin Cytoskeleton Organization Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Positive Regulation Of Phosphorylation Neutrophil Degranulation Positive Regulation Of JNK Cascade Ephrin Receptor Signaling Pathway Positive Regulation Of Exosomal Secretion Positive Regulation Of Extracellular Exosome Assembly	Startle Response Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport
Pathways		Ephrin signaling Neurofascin interactions Neutrophil degranulation	Voltage gated Potassium channels
Drugs			Imipramine Astemizole
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379)
Interacting Genes		173 interacting genes: ABI2 ANKRD40 ANP32B APIP BCL2L15 C11orf68 C1orf109 CADM1 CADPS CALCOCO2 CBR3 CBY2 CCDC102B CD6 CD63 CDA CDC34 CDCP1 CDIPT CEP55 CGGBP1 CLK2 CLK3 CMTM5 COX4I1 CRYAA CT45A3 CT45A5 CUTC DCTD DCTPP1 DMC1 DRAP1 DTNBP1 EAF1 EDARADD EFNB1 EFNB2 EIF1AD EIF5A2 ELAVL1 ENOX1 ENTR1 EPHB2 ERICH2 FAM118A FAM118B FAM9B FLAD1 FOXP2 FTH1 FTL GNMT GPATCH11 GPR37 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRM2 GRM3 GRM7 HIVEP1 HMGB3 HNRNPC HOMEZ HOXA1 HPRT1 HSBP1 IHO1 IKZF1 IL5RA INO80E KCNH1 KCTD1 KCTD6 KCTD9 KHDRBS2 KLHL12 KLHL2 KRTAP10-3 KRTAP10-7 KRTAP5-9 LDOC1 LGALS2 LSM6 LZTFL1 MAD2L1 MAPRE3 MBD3 MED4 MID2 MRFAP1L1 MTUS2 NADK NAGK NECAB2 NF2 NFASC NKAPD1 NOTCH2NLA NT5C2 OSTF1 PDCD6IP PDE4DIP PHC2 PNMA1 PNMA2 PRPF38A PRPF40A PRR13 PSMC6 PSTPIP1 PTEN PTPRJ PTS PUF60 PYCR3 RAB5A RBM39 REEP6 REL RIC8A RNF11 RNH1 ROPN1 RP9P RPL22 RTN1 RUNDC3A SDC1 SDC2 SDC4 SDCBP2 SEPTIN3 SET SIAH1 SLC6A5 SMARCA2 SOX4 SREK1IP1 SRSF11 SRSF7 SSNA1 STX1A SULT1B1 TDO2 TEKT1 TFCP2 TGFA THG1L TIFA TKFC TLE5 TMEM239 TNFAIP8 TRAF5 TRIM27 TRIM32 TRIM38 TRIM54 UBC UBE2A ULK1 WASHC3 WASL WDR91 ZBTB14 ZBTB8A ZCCHC10 ZCCHC17	10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP
Entrez ID		6386	3756
HPRD ID		03741	04492
Ensembl ID		ENSG00000137575	ENSG00000143473
Uniprot IDs		A0A024R7Z5 B4DHN5 G5EA09 O00560	O95259
PDB IDs		1N99 1NTE 1OBX 1OBY 1OBZ 1R6J 1V1T 1W9E 1W9O 1W9Q 1YBO 4Z33	5J7E
Enriched GO Terms of Interacting Partners?
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