KCNH1 and KCNC1

Number of citations of the paper that reports this interaction (PubMedID 12060745)
50

Data Source:
BioGRID (two hybrid)

		KCNH1	KCNC1
Description		potassium voltage-gated channel subfamily H member 1	potassium voltage-gated channel subfamily C member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Cell Junction Dendrite Axolemma Early Endosome Membrane Perikaryon Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Postsynaptic Density Membrane Integral Component Of Presynaptic Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Cell Junction Axon Axolemma Dendrite Membrane Neuronal Cell Body Membrane Neuronal Cell Body Calyx Of Held Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Protein Kinase Binding Cyclic Nucleotide Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding 14-3-3 Protein Binding Phosphatidylinositol Bisphosphate Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Kinesin Binding Ion Channel Binding Voltage-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential
	Biological Process	Startle Response Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport	Potassium Ion Transport Response To Toxic Substance Response To Light Intensity Response To Auditory Stimulus Response To Amine Cerebellum Development Globus Pallidus Development Cellular Response To Drug Response To Potassium Ion Protein Homooligomerization Protein Tetramerization Response To Fibroblast Growth Factor Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Positive Regulation Of Voltage-gated Potassium Channel Activity Response To Nerve Growth Factor
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Imipramine Astemizole	Dalfampridine
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379)	Body mass index ( 26426971) Night sleep phenotypes ( 27126917) Opioid sensitivity ( 24143882)
Interacting Genes		10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP	4 interacting genes: ANK3 KCNG3 KCNH1 KCNV2
Entrez ID		3756	3746
HPRD ID		04492	15936
Ensembl ID		ENSG00000143473	ENSG00000129159
Uniprot IDs		O95259	P48547 Q3KNS8
PDB IDs		5J7E
Enriched GO Terms of Interacting Partners?
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