SCNN1A and COMMD10

Number of citations of the paper that reports this interaction (PubMedID 29997525)
1

Data Source:
BioGRID (pull down)

		SCNN1A	COMMD10
Description		sodium channel epithelial 1 subunit alpha	COMM domain containing 10
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Motile Cilium Sodium Channel Complex Ciliary Membrane Extracellular Exosome Sperm Principal Piece	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding
	Biological Process	Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis
Pathways		Stimuli-sensing channels	Neddylation
Drugs		Triamterene Amiloride
Diseases		Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Bronchiectasis with or without elevated sweat chloride
GWAS		Adverse response to drug ( 30420678) Alopecia areata ( 25608926) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity (early onset extreme) ( 23563609) Primary biliary cirrhosis ( 22961000)	Ankle-brachial index ( 31388106) Asthma or chronic obstructive pulmonary disease ( 24993907) Bipolar disorder and schizophrenia ( 22688191) Inflammatory biomarkers ( 22228203) Metabolite levels (X-11787) ( 23934736)
Interacting Genes		18 interacting genes: COMMD10 CSNK2A1 EPN1 HECW1 ITCH NEDD4 NEDD4L NPC2 SCNN1B SCNN1G SERP1 SNX3 STX1A TSG101 UBE2I USP10 WWP1 WWP2	4 interacting genes: COMMD1 SCNN1A SCNN1B SCNN1G
Entrez ID		6337	51397
HPRD ID		02575	16734
Ensembl ID		ENSG00000111319	ENSG00000145781
Uniprot IDs		P37088	D6RJ90 Q9Y6G5
PDB IDs		2M3O 6BQN
Enriched GO Terms of Interacting Partners?
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