RSU1 and LIMS1

Number of citations of the paper that reports this interaction (PubMedID 15878342)
39

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		RSU1	LIMS1
Description		Ras suppressor protein 1	LIM zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Focal Adhesion Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding
	Biological Process	Signal Transduction Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of GTPase Activity	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Cell Junction Assembly Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Initial alcohol sensitivity ( 30276832) Major depressive disorder ( 29317602) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave. ( 28394258) Urinary albumin excretion ( 21355061) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) LDL cholesterol ( 30275531) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		5 interacting genes: APP GSK3B HGS LIMS1 RAF1	14 interacting genes: DAPK1 EHMT2 FERMT2 FERMT3 ILK LPXN MBIP NCK2 PARVA RBBP8 RSU1 SMURF1 TGFBR1 TMSB4X
Entrez ID		6251	3987
HPRD ID		01551	03978
Ensembl ID		ENSG00000148484	ENSG00000169756
Uniprot IDs		Q15404	P48059
PDB IDs			1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF
Enriched GO Terms of Interacting Partners?
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