BDKRB2 and GRK3

Number of citations of the paper that reports this interaction (PubMedID 11517230)
15

Data Source:
HPRD (in vivo, in vitro)

		BDKRB2	GRK3
Description		bradykinin receptor B2	G protein-coupled receptor kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Endosome Plasma Membrane Integral Component Of Plasma Membrane	Cytosol Plasma Membrane
	Molecular Function	Protease Binding Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Type 1 Angiotensin Receptor Binding Protein Heterodimerization Activity	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity Protein Binding ATP Binding Beta-adrenergic Receptor Kinase Activity
	Biological Process	Smooth Muscle Contraction Inflammatory Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Response To Salt Stress Regulation Of Vasoconstriction Negative Regulation Of Peptidyl-serine Phosphorylation Vasoconstriction Vasodilation Regulation Of Vascular Permeability Arachidonic Acid Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator	Protein Phosphorylation Signal Transduction G Protein-coupled Receptor Signaling Pathway Receptor Internalization
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	G alpha (s) signalling events Cargo recognition for clathrin-mediated endocytosis
Drugs		Anatibant Icatibant	ATP
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Corneal astigmatism ( 30306274) Gout ( 22179738) Mumps ( 28928442) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		12 interacting genes: ACE AGTR1 GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 NOS1 NOS3 PRKCD PTPN11	10 interacting genes: ADRB2 AGTR1 BDKRB2 CCR4 CCR5 CXCR4 GIT1 HSPB1 OPRM1 SMURF1
Entrez ID		624	157
HPRD ID		00213	00183
Ensembl ID		ENSG00000168398	ENSG00000100077
Uniprot IDs		P30411	A0A024R1D8 P35626 Q8N433
PDB IDs
Enriched GO Terms of Interacting Partners?
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