RPS27 and PPBP

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RPS27	PPBP
Description		ribosomal protein S27	pro-platelet basic protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ribosome Postsynaptic Density Cytosolic Small Ribosomal Subunit	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Protein Binding Zinc Ion Binding	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Platelet Degranulation Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Leukocyte Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Major pathway of rRNA processing in the nucleolus and cytosol Mitotic Prometaphase Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency EML4 and NUDC in mitotic spindle formation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic Acid Copper
Diseases
GWAS			Metabolite levels ( 22916037)
Interacting Genes		14 interacting genes: ACTN1 ACTN4 APC ENOPH1 ENTPD4 MARS1 NACAD NSG2 PPBP PTEN RTN4 SKIL TOM1 WDCP	20 interacting genes: CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		6232	5473
HPRD ID		04744	07171
Ensembl ID		ENSG00000177954	ENSG00000163736
Uniprot IDs		P42677	P02775
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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