RPS3A and SAP18

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPS3A	SAP18
Description		ribosomal protein S3A	Sin3A associated protein 18
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Cytosolic Small Ribosomal Subunit Synapse Extracellular Exosome Ribonucleoprotein Complex	Histone Deacetylase Complex Nucleoplasm Cytosol Nuclear Body Nuclear Speck Exon-exon Junction Complex ASAP Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding	Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Cell Differentiation Negative Regulation Of Apoptotic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	HDACs deacetylate histones NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		HDL cholesterol ( 20686565)
Interacting Genes		17 interacting genes: ATF7IP C11orf49 CCDC50 CHN1 CREB3 DDIT3 EDEM2 FANCC HGS HSP90AA1 NEDD4 PARP1 SAP18 SOD2 TOE1 UBE2I VDAC2	12 interacting genes: HDAC1 IKZF1 INCA1 NOL12 POLE2 RBM39 RNPS1 RPS3A SIN3A SUFU TADA3 TSC22D2
Entrez ID		6189	10284
HPRD ID		01606	04256
Ensembl ID		ENSG00000145425	ENSG00000150459
Uniprot IDs		B7Z3M5 P61247	O00422
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	2HDE
Enriched GO Terms of Interacting Partners?
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