RPN1 and UBQLN2

Number of citations of the paper that reports this interaction (PubMedID 12200120)
45

Data Source:
HPRD (in vitro, in vivo)

		RPN1	UBQLN2
Description		ribophorin I	ubiquilin 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Cytosol Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane Melanosome	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	RNA Binding Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Protein Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Cellular Protein Modification Process Protein N-linked Glycosylation Via Asparagine	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly
Pathways		SRP-dependent cotranslational protein targeting to membrane Asparagine N-linked glycosylation	Cargo recognition for clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil counts ( 29403010 27863252) Mild to moderate chronic kidney disease ( 31178898) Monocyte count ( 23314186 29403010 27863252) Monocyte percentage of white cells ( 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 21738480) White blood cell count (basophil) ( 29403010)
Interacting Genes		15 interacting genes: ADRM1 DPF1 ERBB3 HSPA5 RAB7A RAD23A RBBP4 SGTA SIGIRR SMARCB1 UBC UBQLN1 UBQLN2 UBQLN4 WSB2	22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4
Entrez ID		6184	29978
HPRD ID		01598	02224
Ensembl ID		ENSG00000163902	ENSG00000188021
Uniprot IDs		P04843	Q9UHD9
PDB IDs			1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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