UBQLN2 and HSPA13

Number of citations of the paper that reports this interaction (PubMedID 10675567)
35

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, two hybrid)

		UBQLN2	HSPA13
Description		ubiquilin 2	heat shock protein family A (Hsp70) member 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Autophagosome Cytosol Plasma Membrane Cytoplasmic Vesicle	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Polyubiquitin Modification-dependent Protein Binding	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Autophagosome Assembly Ubiquitin-dependent Protein Catabolic Process Regulation Of Macroautophagy Ubiquitin-dependent ERAD Pathway Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagosome Assembly	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding
Pathways		Cargo recognition for clathrin-mediated endocytosis	Regulation of HSF1-mediated heat shock response
Drugs			Copper
Diseases
GWAS
Interacting Genes		22 interacting genes: ADRM1 ATXN7 BTRC C1QA CD93 FBXO25 FUS HERC3 HERPUD1 HNRNPA3 HSPA13 MTNR1B PRPF40A PSMA2 PSMA5 PSMD4 RNF11 RPN1 SMURF1 UBC UBE3A UBQLN4	8 interacting genes: BAG6 POLE4 RMI1 SGTA SSR1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		29978	6782
HPRD ID		02224	03061
Ensembl ID		ENSG00000188021	ENSG00000155304
Uniprot IDs		Q9UHD9	A0A140VK72 P48723
PDB IDs		1J8C 2NBV 6MUN
Enriched GO Terms of Interacting Partners?
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