RPL38 and AP2M1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPL38	AP2M1
Description		ribosomal protein L38	adaptor related protein complex 2 subunit mu 1
Image
GO Annotations	Cellular Component	Cytosol Focal Adhesion Postsynaptic Density Cytosolic Large Ribosomal Subunit Eukaryotic 80S Initiation Complex Polysomal Ribosome	Lysosomal Membrane Cytosol Plasma Membrane Clathrin-coated Pit AP-2 Adaptor Complex Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Endolysosome Membrane Clathrin-coated Endocytic Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome	Signal Sequence Binding Protein Binding Lipid Binding Clathrin Adaptor Activity Ion Channel Binding Low-density Lipoprotein Particle Receptor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Skeletal System Development Ossification Cytoplasmic Translation Translation Translational Initiation Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Sensory Perception Of Sound Viral Transcription Ribonucleoprotein Complex Assembly 90S Preribosome Assembly Middle Ear Morphogenesis Axial Mesoderm Development	Intracellular Protein Transport Vesicle Budding From Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Receptor Internalization Low-density Lipoprotein Particle Receptor Catabolic Process Low-density Lipoprotein Particle Clearance Cellular Protein-containing Complex Assembly Ephrin Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Wnt Signaling Pathway, Planar Cell Polarity Pathway Membrane Organization Clathrin-dependent Endocytosis Regulation Of Vesicle Size Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Nef mediated downregulation of CD28 cell surface expression Nef Mediated CD4 Down-regulation Retrograde neurotrophin signalling Retrograde neurotrophin signalling Nef Mediated CD8 Down-regulation Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance
Drugs
Diseases
GWAS		Depression in smokers ( 30219690) Polymyositis ( 26362759)	Major depressive disorder ( 22472876)
Interacting Genes		3 interacting genes: AP2M1 CHMP5 PTEN	51 interacting genes: ADRA1B AP2B1 AQP4 ARRB2 ATXN1L CACNA1A CD22 CD3D CDK11B CKS1B CORO7 CRIP1 CSNK2B CTLA4 DAB2 DCX DNAJB11 DPPA2 DVL2 EHD2 EIF4G1 ETV5 FGF12 FURIN FXR2 GAK GRIN2B IKZF1 IL1RAP JADE1 KCNJ11 LAMP1 LPP LY9 MED4 MEGF10 NCOR2 NDRG1 RALBP1 RPL38 RRP12 RSPH14 RUNDC3A STON2 SYNJ1 TASOR TBC1D5 TGOLN2 UBC XPA ZBTB8A
Entrez ID		6169	1173
HPRD ID		16048	03014
Ensembl ID		ENSG00000172809	ENSG00000161203
Uniprot IDs		A0A024R8P8 P63173	B4DNB9 E9PFW3 Q96CW1
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	1H6E 6BNT
Enriched GO Terms of Interacting Partners?
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