EXOC4 and EXOC7

Number of citations of the paper that reports this interaction (PubMedID 12687004)
128

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		EXOC4	EXOC7
Description		exocyst complex component 4	exocyst complex component 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cell Cytoplasm Cytosol Plasma Membrane Microvillus Membrane Growth Cone Membrane Myelin Sheath Abaxonal Region Synapse Flemming Body	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	Protein Binding Ral GTPase Binding PDZ Domain Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Chemical Synaptic Transmission Regulation Of Macroautophagy Paraxial Mesoderm Formation Vesicle Tethering Involved In Exocytosis	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Food allergy ( 29030101) General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Moderate to vigorous physical activity levels ( 29899525) Mood instability ( 31168069) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) QT interval ( 29213071) Response to selective serotonin reuptake inhibitors in depression ( 30034349) Tonometry ( 17903302) Vigorous physical activity ( 29899525)
Interacting Genes		9 interacting genes: BIRC6 CEP63 DISC1 DLG3 DLG4 DLGAP4 EXOC7 GRIN2B RALA	25 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14
Entrez ID		60412	23265
HPRD ID		12185	16292
Ensembl ID		ENSG00000131558	ENSG00000182473
Uniprot IDs		Q6NX51 Q96A65	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs
Enriched GO Terms of Interacting Partners?
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