RHEB and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 17928295)
87

Data Source:
BioGRID (two hybrid)

		RHEB	RABAC1
Description		Ras homolog, mTORC1 binding	Rab acceptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Spliceosomal Complex Lysosomal Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Membrane Extracellular Exosome	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Kinase Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding
	Biological Process	Cell Cycle Arrest Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Positive Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Cold-induced Thermogenesis Regulation Of Type B Pancreatic Cell Development
Pathways		Macroautophagy mTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF CREB3 ECSIT FKBP8 HTT MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RNF152 RPS6KB1 RPTOR TSC1 TSC2 USP4	65 interacting genes: CMTM3 COQ8A CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LMNA LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 S100B SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		6009	10567
HPRD ID		03188	05375
Ensembl ID		ENSG00000106615	ENSG00000105404
Uniprot IDs		A0A090N900 Q15382	Q9UI14
PDB IDs		1XTQ 1XTR 1XTS 3SEA 3T5G 5YXH 6BCU 6BSX 6BT0
Enriched GO Terms of Interacting Partners?
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