RGS7 and CHRM5

Number of citations of the paper that reports this interaction (PubMedID 19182865)
28

Data Source:
BioGRID (pull down)

		RGS7	CHRM5
Description		regulator of G protein signaling 7	cholinergic receptor muscarinic 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Synapse Postsynaptic Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity G-protein Beta-subunit Binding	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Protein Folding G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Intracellular Signal Transduction Positive Regulation Of GTPase Activity	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Muscarinic acetylcholine receptors G alpha (q) signalling events
Drugs			Ziprasidone Amitriptyline Olanzapine Metixene Terfenadine Clozapine Trihexyphenidyl Loxapine Promazine Pethidine Imipramine Gallamine Triethiodide Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine Methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Cryptenamine Brompheniramine Maprotiline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone
Diseases
GWAS		Chronotype ( 30696823) Diastolic blood pressure ( 29208002) Ischemic stroke (cardioembolic) ( 29531354) Longevity (90 years and older) ( 25199915) Major depressive disorder ( 27479909) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Western dietary pattern ( 28644415)
Interacting Genes		16 interacting genes: CHRM1 CHRM2 CHRM3 CHRM5 GNAI1 GNAI3 GNAO1 GNAQ GNAZ GNB5 MSX1 PKD1 PRKCA SNAPIN YWHAB YWHAQ	2 interacting genes: GPRASP1 RGS7
Entrez ID		6000	1133
HPRD ID		03948	00331
Ensembl ID		ENSG00000182901	ENSG00000184984
Uniprot IDs		B7Z223 B7Z257 P49802	A0A024R9I2 P08912 Q8IVW0
PDB IDs		2A72 2D9J
Enriched GO Terms of Interacting Partners?
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