CHRM5 and RGS7

Number of citations of the paper that reports this interaction (PubMedID 19182865)
28

Data Source:
BioGRID (pull down)

		CHRM5	RGS7
Description		cholinergic receptor muscarinic 5	regulator of G protein signaling 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Synapse Postsynaptic Membrane	Cytosol Plasma Membrane
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding G Protein-coupled Acetylcholine Receptor Activity Neurotransmitter Receptor Activity	GTPase Activity GTPase Activator Activity G-protein Beta-subunit Binding
	Biological Process	Gastric Acid Secretion G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Chemical Synaptic Transmission Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation G Protein-coupled Serotonin Receptor Signaling Pathway	Protein Folding G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Intracellular Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Muscarinic acetylcholine receptors G alpha (q) signalling events	G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs		Ziprasidone Amitriptyline Olanzapine Metixene Terfenadine Clozapine Trihexyphenidyl Loxapine Promazine Pethidine Imipramine Gallamine Triethiodide Darifenacin Nortriptyline Amoxapine Cinnarizine Atropine Nicardipine Paroxetine Homatropine Methylbromide Trimipramine Scopolamine Benzquinamide Propiomazine Cryptenamine Brompheniramine Maprotiline Tolterodine Promethazine Doxepin Desipramine Ketamine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Tiotropium Solifenacin ALKS 27 Fesoterodine Aclidinium Umeclidinium Dosulepin Etoperidone
Diseases
GWAS			Chronotype ( 30696823) Diastolic blood pressure ( 29208002) Ischemic stroke (cardioembolic) ( 29531354) Longevity (90 years and older) ( 25199915) Major depressive disorder ( 27479909) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Western dietary pattern ( 28644415)
Interacting Genes		2 interacting genes: GPRASP1 RGS7	16 interacting genes: CHRM1 CHRM2 CHRM3 CHRM5 GNAI1 GNAI3 GNAO1 GNAQ GNAZ GNB5 MSX1 PKD1 PRKCA SNAPIN YWHAB YWHAQ
Entrez ID		1133	6000
HPRD ID		00331	03948
Ensembl ID		ENSG00000184984	ENSG00000182901
Uniprot IDs		A0A024R9I2 P08912 Q8IVW0	B7Z223 B7Z257 P49802
PDB IDs			2A72 2D9J
Enriched GO Terms of Interacting Partners?
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