BCKDHB and BCKDK

		BCKDHB	BCKDK
Description		branched chain keto acid dehydrogenase E1 subunit beta	branched chain keto acid dehydrogenase kinase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex	Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
	Molecular Function	Alpha-ketoacid Dehydrogenase Activity 3-methyl-2-oxobutanoate Dehydrogenase (2-methylpropanoyl-transferring) Activity Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
	Biological Process	Response To Nutrient Branched-chain Amino Acid Catabolic Process Oxidation-reduction Process	Protein Phosphorylation Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Phosphorylation Glucose Homeostasis Negative Regulation Of Pyruvate Dehydrogenase Activity
Pathways		Glyoxylate metabolism and glycine degradation Branched-chain amino acid catabolism	Branched-chain amino acid catabolism
Drugs			Adenosine 5'-[Î³-thio]triphosphate
Diseases		Maple syrup urine disease (MSUD)
GWAS		Adolescent idiopathic scoliosis ( 31417091) Diastolic blood pressure ( 30224653) Height ( 28552196 25282103 23563607 31562340) Joint mobility (Beighton score) ( 27182965) Prudent dietary pattern ( 28644415) Sitting height ratio ( 25865494) Spine bone size ( 31053729) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Parkinson's disease ( 25064009)
Interacting Genes		2 interacting genes: BCKDHA BCKDK	17 interacting genes: APP BCKDHB CDIPT EIF3C EPS8 FBXO7 FOXO1 GUCA1A LSM8 NR5A2 PCDHB9 QPRT SETD1A STAT3 TAOK2 TRAF4 ZNF267
Entrez ID		594	10295
HPRD ID		02011	12523
Ensembl ID		ENSG00000083123	ENSG00000103507
Uniprot IDs		A0A140VKB3 B4E2N3 B7ZB80 P21953	A0A024QZA9 O14874
PDB IDs		1DTW 1OLS 1OLU 1OLX 1U5B 1V11 1V16 1V1M 1V1R 1WCI 1X7W 1X7X 1X7Y 1X7Z 1X80 2BEU 2BEV 2BEW 2BFB 2BFC 2BFD 2BFE 2BFF 2J9F
Enriched GO Terms of Interacting Partners?
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