RBM4 and U2AF2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		RBM4	U2AF2
Description		RNA binding motif protein 4	U2 small nuclear RNA auxiliary factor 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck	Commitment Complex Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Prespliceosome U2AF
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Cyclin Binding MiRNA Binding Pre-mRNA Intronic Binding Pre-mRNA Intronic Pyrimidine-rich Binding	RNA Binding Protein Binding Poly-pyrimidine Tract Binding Enzyme Binding Pre-mRNA 3'-splice Site Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA RNA Processing Negative Regulation Of Translation Cell Differentiation Negative Regulation Of Translation In Response To Stress MiRNA Mediated Inhibition Of Translation Entrainment Of Circadian Clock By Photoperiod MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Translational Initiation Response To Arsenic-containing Substance Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Muscle Cell Differentiation Circadian Regulation Of Translation	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Negative Regulation Of Protein Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		Circadian Clock	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Menopause (age at onset) ( 26414677)
Interacting Genes		31 interacting genes: AQR CCNA1 CDK2 CXorf56 DDX17 DDX5 DHX9 ESS2 HNRNPF HNRNPH2 HNRNPH3 HNRNPK HNRNPM HNRNPUL1 KLHL41 LRP2BP MAPK8IP2 PABPC1 PRPF31 PTBP2 RBM10 RBM22 RBM23 RBM42 RBM7 SF1 SF3B4 SMAD5 SNRPC TRIB3 U2AF2	47 interacting genes: APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA IL7R KHDC4 KHDRBS3 LURAP1 MAP1B OTUB2 PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TLE5 TOP1 U2AF1 WT1 ZRSR2
Entrez ID		5936	11338
HPRD ID		03982	01872
Ensembl ID		ENSG00000173933	ENSG00000063244
Uniprot IDs		Q9BWF3	P26368
PDB IDs		2DNQ	1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW 4TU7 4TU8 4TU9 5EV1 5EV2 5EV3 5EV4 5W0G 5W0H
Enriched GO Terms of Interacting Partners?
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