RAD23B and NGLY1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		RAD23B	NGLY1
Description		RAD23 homolog B, nucleotide excision repair protein	N-glycanase 1
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GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytosol XPC Complex	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding
	Biological Process	Nucleotide-excision Repair, DNA Damage Recognition Nucleotide-excision Repair, DNA Duplex Unwinding Nucleotide-excision Repair Nucleotide-excision Repair, Preincision Complex Assembly Protein Folding Spermatogenesis Protein Deubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Global Genome Nucleotide-excision Repair Cellular Response To Interleukin-7	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER	N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases
GWAS		Body mass index ( 20966902) Breast cancer ( 21263130) Chronotype ( 30696823) Cutaneous malignant melanoma ( 26237428) Melanoma ( 28212542) Prostate cancer ( 23023329)
Interacting Genes		23 interacting genes: ADRM1 ATXN3 CALM1 DBI DEAF1 HMGB1 MLH1 MPG NGLY1 PAQR3 PAX3 PNMA5 PSMC2 PSMD4 PUF60 RPA1 TDG UBA2 UBB UBC UBE3A XPC ZFAND5	19 interacting genes: APP FAF1 GJB2 GRM7 GUCD1 LIMD1 MAP3K2 NSFL1C OPA3 PROC RAD23A RAD23B SH3BP1 SRPK2 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP
Entrez ID		5887	55768
HPRD ID		06772	10118
Ensembl ID		ENSG00000119318	ENSG00000151092
Uniprot IDs		B7Z4W4 P54727	Q96IV0
PDB IDs		1P1A 1PVE 1UEL	2CCQ 2CM0
Enriched GO Terms of Interacting Partners?
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