RAD9A and ATAD5

Number of citations of the paper that reports this interaction (PubMedID 15983387)
10

Data Source:
HPRD (in vitro)

		RAD9A	ATAD5
Description		RAD9 checkpoint clamp component A	ATPase family AAA domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Checkpoint Clamp Complex	Nucleus Elg1 RFC-like Complex
	Molecular Function	Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity SH3 Domain Binding Enzyme Binding Protein Kinase Binding Histone Deacetylase Binding	DNA Binding Protein Binding ATP Binding DNA Clamp Unloader Activity
	Biological Process	DNA Replication Checkpoint DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Positive Regulation Of B Cell Proliferation Nuclear DNA Replication B Cell Proliferation Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Isotype Switching Positive Regulation Of DNA Replication Positive Regulation Of Isotype Switching To IgG Isotypes Nucleic Acid Phosphodiester Bond Hydrolysis DNA Clamp Unloading Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Cell Cycle G2/M Phase Transition
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth weight ( 31043758) Body mass index ( 28892062) Breast cancer ( 25751625 29059683) Diastolic blood pressure ( 30224653) Granulocyte percentage of myeloid white cells ( 27863252) Height ( 23563607 18391951) Hip circumference adjusted for BMI ( 25673412) Lung cancer in ever smokers ( 28604730) Mean platelet volume ( 27863252) Neutrophil percentage of white cells ( 27863252) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28552196 28448500)
Interacting Genes		38 interacting genes: ABL1 AR ATAD5 ATM BCL2 BCL2L1 CAD CHEK2 CLSPN COPS5 CSNK2A1 CSNK2A2 DNAJC7 FEM1B FEN1 HDAC1 HUS1 HUS1B ITSN2 MLH1 MSH2 MSH3 MSH6 NR3C1 OGG1 PCNA POLB PRKCE RAD17 RAD9B RHNO1 RPA1 RPA2 SF3B3 TDG TLK1 TOPBP1 WRN	2 interacting genes: PCNA RAD9A
Entrez ID		5883	79915
HPRD ID		04788	07792
Ensembl ID		ENSG00000172613	ENSG00000176208
Uniprot IDs		Q99638	Q96QE3
PDB IDs		3A1J 3G65 3GGR 6HM5
Enriched GO Terms of Interacting Partners?
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