RAD9A and HUS1B

Number of citations of the paper that reports this interaction (PubMedID 11944979)
9

Data Source:
HPRD (in vivo)

		RAD9A	HUS1B
Description		RAD9 checkpoint clamp component A	HUS1 checkpoint clamp component B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Checkpoint Clamp Complex	Nucleolus Checkpoint Clamp Complex Site Of Double-strand Break
	Molecular Function	Protein Binding 3'-5' Exonuclease Activity Exodeoxyribonuclease III Activity SH3 Domain Binding Enzyme Binding Protein Kinase Binding Histone Deacetylase Binding
	Biological Process	DNA Replication Checkpoint DNA Damage Checkpoint DNA Replication DNA Repair Cellular Response To DNA Damage Stimulus Intra-S DNA Damage Checkpoint Cellular Response To Ionizing Radiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Telomere Maintenance Double-strand Break Repair Via Homologous Recombination Nucleotide-excision Repair Intra-S DNA Damage Checkpoint Mitotic DNA Replication Checkpoint Meiotic DNA Integrity Checkpoint
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Aging ( 22773346) Metabolite levels ( 23823483)
Interacting Genes		38 interacting genes: ABL1 AR ATAD5 ATM BCL2 BCL2L1 CAD CHEK2 CLSPN COPS5 CSNK2A1 CSNK2A2 DNAJC7 FEM1B FEN1 HDAC1 HUS1 HUS1B ITSN2 MLH1 MSH2 MSH3 MSH6 NR3C1 OGG1 PCNA POLB PRKCE RAD17 RAD9B RHNO1 RPA1 RPA2 SF3B3 TDG TLK1 TOPBP1 WRN	4 interacting genes: HUS1 RAD1 RAD9A RAD9B
Entrez ID		5883	135458
HPRD ID		04788	13722
Ensembl ID		ENSG00000172613	ENSG00000188996
Uniprot IDs		Q99638	Q8NHY5
PDB IDs		3A1J 3G65 3GGR 6HM5
Enriched GO Terms of Interacting Partners?
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