RAC1 and MYD88

  • Number of citations of the paper that reports this interaction (PubMedID 11416133)
  • 18
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology)

RAC1

MYD88

Description Rac family small GTPase 1 MYD88 innate immune signal transduction adaptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Basal cell carcinoma ( 31174203)
  • Body mass index ( 26426971)
  • Coronary artery disease ( 29212778)
  • Keratinocyte cancer (MTAG) ( 31174203)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Red cell distribution width ( 27863252)
  • Gut microbiota (bacterial taxa) ( 27723756)
  • Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes 153 interacting genes: ACTA1 ACTB AGAP1 AGAP2 AKT1 ARFIP2 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP27 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP44 ARHGDIA ARHGDIB ARHGDIG ARHGEF2 ARHGEF25 ARHGEF4 ARHGEF7 ARL2BP BAG6 BAIAP2 BCR BIRC2 BRINP1 CASP3 CASP7 CAV1 CDC23 CDC42BPG CDC42SE1 CDC42SE2 CFAP36 CHN1 CHN2 CIT COG5 CORO1C CSN2 CYBA CYBB CYFIP1 DEF6 DIAPH1 DIAPH3 DMPK DOCK1 DOCK2 DOCK7 DOCK8 DVL1 DVL2 EIF2AK2 ENAH FHOD1 FLNA FMN2 FMNL1 GRN HACD3 HACE1 HPS4 ICMT IFNGR1 IL1RAP IQGAP1 IQGAP2 KPNA4 KPNA6 KRT40 KTN1 LATS1 LRP2 LTBP3 LTBP4 LZTS2 MAGI1 MAP3K10 MAP3K11 MAP3K4 MCF2L MCM3AP METAP2 MT-CO3 MTNR1A MYD88 MYH9 NCF2 NCK1 NCKAP1 NEDD4 NME1 NOS2 NOXA1 NR2C2 OCRL OPHN1 PAK1 PAK2 PAK3 PAK5 PAK6 PARD6A PARD6B PARD6G PIAS3 PIK3R1 PIP4K2A PLD1 PLEKHG2 PLXNB1 PPP2R2B PRKCA PRKCD PRKCI PRKN PRMT6 PTK2 RALBP1 RAP1GDS1 RASGRF1 RCC2 RGL2 RPS6KB1 SET SFPQ SH3BP1 SH3RF1 SH3RF3 SNX31 STAT1 STAT3 STAU1 SYNJ2 TBC1D3F TIAM1 TLR2 TNFRSF12A TRIO TUBA4A UBC UNKL USH1C USP6 VAV1 VAV2 VAV3 VWF WAS WASF1 40 interacting genes: BTK CD93 CISH FADD FLII IKBKG IL1R1 IL1RAP IL1RL1 IRAK1 IRAK2 IRAK3 IRAK4 IRF4 IRF5 IRF7 MAL MBIP MDM2 PELI2 PFKL POLR1C PRDX1 RAC1 SARM1 SIAH1 SIAH2 SMAD3 SPOP STAP2 TIRAP TLR10 TLR2 TLR3 TLR4 TLR5 TLR7 TLR8 TXN USP7
Entrez ID 5879 4615
HPRD ID 03627 03703
Ensembl ID ENSG00000136238 ENSG00000172936
Uniprot IDs A4D2P0 A4D2P1 P63000 A0A0A0MS70 A0A0A0MSI9 A0A3B3ITY3 A0A3F2YP85 H0Y4G9 Q99836
PDB IDs 1E96 1FOE 1G4U 1HE1 1HH4 1I4D 1I4L 1I4T 1MH1 1RYF 1RYH 2FJU 2H7V 2NZ8 2P2L 2RMK 2VRW 2WKP 2WKQ 2WKR 2YIN 3B13 3BJI 3RYT 3SBD 3SBE 3SU8 3SUA 3TH5 4GZL 4GZM 4YON 5FI0 5HZH 5N6O 5O33 6AGP 6BC1 2JS7 2Z5V 3MOP 4DOM 4EO7 6I3N
Enriched GO Terms of Interacting Partners?
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