DMRT3 and UBASH3B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DMRT3	UBASH3B
Description		doublesex and mab-3 related transcription factor 3	ubiquitin associated and SH3 domain containing B
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Tyrosine Phosphatase Activity Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Phosphoprotein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Signal Transduction Peptidyl-tyrosine Dephosphorylation Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Regulation Of Protein Binding Regulation Of Osteoclast Differentiation Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Aggregation Negative Regulation Of Platelet Aggregation
Pathways
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Response to Homoharringtonine (cytotoxicity) ( 25628645)	Blood protein levels ( 30072576) Blood urea nitrogen levels ( 31152163) Cholesterol, total ( 24097068 25961943 20686565) Chronotype ( 30696823) Diastolic blood pressure ( 30224653) Eye length ( 30174134) HDL cholesterol ( 24097068 20686565) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Pemphigus vulgaris ( 29857070) Stroke ( 26089329) Systolic blood pressure ( 30578418) Total cholesterol levels ( 28334899)
Interacting Genes		26 interacting genes: CCNDBP1 INCA1 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 MDFI MGAT5B MID2 MTUS2 NOTCH2NLA PLSCR1 PSMA3 RBPMS REL SAT1 TCF4 TRAF1 TRIM23 TRIM27 TRIP6 UBASH3B	27 interacting genes: CBL CBLB CUL3 DAZAP2 DMRT3 DOC2A FAM168A JAK2 KHDRBS1 MAP3K1 PKP4 PRKN RCHY1 RNF41 SHC1 SLC25A48 SPRY2 SYK UBB UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H VPS37B
Entrez ID		58524	84959
HPRD ID		16827	16463
Ensembl ID		ENSG00000064218	ENSG00000154127
Uniprot IDs		Q9NQL9	Q8TF42
PDB IDs			2CPW 2E5K 5VR6 5W5G
Enriched GO Terms of Interacting Partners?
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