EPS15L1 and FCHO1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, pull down)

		EPS15L1	FCHO1
Description		epidermal growth factor receptor pathway substrate 15 like 1	FCH and mu domain containing endocytic adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding Cadherin Binding	Protein Binding Cytoskeletal Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization	Clathrin Coat Assembly Membrane Organization Clathrin-dependent Endocytosis
Pathways		EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Eosinophil percentage of granulocytes ( 27863252) Lymphocyte counts ( 29403010 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252) White blood cell count ( 27863252 21738480) White matter integrity ( 23218918)	Coronary artery disease ( 29212778)
Interacting Genes		12 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 SGIP1 STON2 TRAPPC2B UBC	17 interacting genes: ACVR1 APP DAB2 DNAJC5 EPS15 EPS15L1 EXOSC5 GDF15 ITSN1 LGALS14 NCK1 PICALM PTK6 SMURF1 SRPK2 ZBTB16 ZNF688
Entrez ID		58513	23149
HPRD ID		09445	16887
Ensembl ID		ENSG00000127527	ENSG00000130475
Uniprot IDs		A0A024R7G6 Q9UBC2	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs
Enriched GO Terms of Interacting Partners?
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