CXCL16 and CXCR6

Number of citations of the paper that reports this interaction (PubMedID 11017100)
151

Data Source:
HPRD (in vivo, in vitro)

		CXCL16	CXCR6
Description		C-X-C motif chemokine ligand 16	C-X-C motif chemokine receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Chemokine Activity	G Protein-coupled Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding C-X-C Chemokine Binding
	Biological Process	Receptor-mediated Endocytosis Chemotaxis G Protein-coupled Receptor Signaling Pathway T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor	Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Genome Replication Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		14 interacting genes: ADAMTSL4 APP CXCR6 KASH5 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LMNA MDFI MTUS2 NOTCH2NLA TMEM239	1 interacting genes: CXCL16
Entrez ID		58191	10663
HPRD ID		16103	05520
Ensembl ID		ENSG00000161921	ENSG00000172215
Uniprot IDs		Q9H2A7	A0N0N3 O00574
PDB IDs
Enriched GO Terms of Interacting Partners?
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