CXCR6 and CXCL16

Number of citations of the paper that reports this interaction (PubMedID 11017100)
151

Data Source:
HPRD (in vivo, in vitro)

		CXCR6	CXCL16
Description		C-X-C motif chemokine receptor 6	C-X-C motif chemokine ligand 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding C-X-C Chemokine Binding	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Chemokine Activity
	Biological Process	Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Genome Replication Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Receptor-mediated Endocytosis Chemotaxis G Protein-coupled Receptor Signaling Pathway T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		1 interacting genes: CXCL16	14 interacting genes: ADAMTSL4 APP CXCR6 KASH5 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LMNA MDFI MTUS2 NOTCH2NLA TMEM239
Entrez ID		10663	58191
HPRD ID		05520	16103
Ensembl ID		ENSG00000172215	ENSG00000161921
Uniprot IDs		A0N0N3 O00574	Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?
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