WFDC1 and FOSL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		WFDC1	FOSL1
Description		WAP four-disulfide core domain 1	FOS like 1, AP-1 transcription factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nuclear Chromatin Nucleus Nucleoplasm Cytosol Presynaptic Membrane Neuron Projection
	Molecular Function	Molecular_function Serine-type Endopeptidase Inhibitor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Cell Growth Negative Regulation Of Endopeptidase Activity Negative Regulation Of Cell Growth Response To Estradiol Response To Drug Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Inflammatory Response Negative Regulation Of Wound Healing	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Chemotaxis Cellular Defense Response Vitellogenesis Female Pregnancy Learning Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Response To Virus Response To Gravity Cellular Response To Extracellular Stimulus Response To Progesterone Response To Cytokine Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Response To Corticosterone Response To CAMP Placenta Blood Vessel Development Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Initiation
Pathways			NGF-stimulated transcription
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Systolic blood pressure (alcohol consumption interaction) ( 24376456) Visceral adipose tissue adjusted for BMI ( 22589738)	Acne (severe) ( 24927181) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Inflammatory bowel disease ( 23128233) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		5 interacting genes: EZR FOSL1 RAB40B XRCC2 ZNF677	24 interacting genes: ATF2 ATF3 ATF4 ATXN1 CALCOCO1 CEBPA CEBPE CEBPG CREB5 DDIT3 DNMT3L EP300 JUN JUNB KPNA1 LDOC1 MAF MAFB NME7 PARVG TAB2 TRIM24 USF1 WFDC1
Entrez ID		58189	8061
HPRD ID		05614	00643
Ensembl ID		ENSG00000103175	ENSG00000175592
Uniprot IDs		Q9HC57	A0A0S2Z595 E9PKL5 E9PPX2 P15407
PDB IDs
Enriched GO Terms of Interacting Partners?
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