PURA and PURB

Number of citations of the paper that reports this interaction (PubMedID 10318844)
30

Data Source:
HPRD (in vivo, in vitro)

		PURA	PURB
Description		purine rich element binding protein A	purine rich element binding protein B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus DNA Replication Factor A Complex Dendrite Cytoplasm Neuronal Cell Body Postsynapse Glutamatergic Synapse	Nucleus Nucleoplasm DNA Replication Factor A Complex
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Double-stranded Telomeric DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding Sequence-specific DNA Binding SMAD Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding Sequence-specific DNA Binding SMAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Unwinding Involved In DNA Replication DNA Replication Initiation Nervous System Development Positive Regulation Of Cell Proliferation Negative Regulation Of Translation Cell Differentiation Lymphocyte Proliferation Epithelial Cell Proliferation Dendritic Transport Of Messenger Ribonucleoprotein Complex	Negative Regulation Of Transcription By RNA Polymerase II Cell Proliferation Cell Differentiation Regulation Of Myeloid Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Platelet count ( 27863252)
Interacting Genes		10 interacting genes: ADAP1 CCNT1 CDK5 E2F1 IL7R PURB RAF1 RB1 SP1 YBX1	3 interacting genes: CSNK2A1 IL7R PURA
Entrez ID		5813	5814
HPRD ID		02721	12325
Ensembl ID		ENSG00000185129	ENSG00000146676
Uniprot IDs		Q00577	Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?
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