HAMP and CKAP4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HAMP	CKAP4
Description		hepcidin antimicrobial peptide	cytoskeleton associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Intercalated Disc Apical Cortex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Hormone Activity	RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cellular Iron Ion Homeostasis Acute-phase Response Immune Response Signal Transduction Aging Response To Iron Ion Response To Zinc Ion Killing Of Cells Of Other Organism Response To Vitamin A Negative Regulation Of Iron Ion Transmembrane Transport Response To Erythropoietin Defense Response To Bacterium Response To Ethanol Defense Response To Fungus Multicellular Organismal Iron Ion Homeostasis Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-6 Cellular Response To Tumor Necrosis Factor Cellular Response To X-ray Liver Regeneration Cellular Response To Bile Acid Negative Regulation Of Intestinal Absorption Response To Iron Ion Starvation	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases		Hemochromatosis (HFE); Juvenile hemochromatosis (JH)
GWAS		Irritable bowel syndrome ( 29673008) Red cell distribution width ( 28957414)	Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: CKAP4 EXOSC5 GLP1R SLC40A1 VKORC1	12 interacting genes: ASCC2 ATF4 DKK1 HAMP MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3
Entrez ID		57817	10970
HPRD ID		05925	16717
Ensembl ID		ENSG00000105697	ENSG00000136026
Uniprot IDs		P81172	A0A024RBH2 Q07065
PDB IDs		1M4E 1M4F 2KEF 3H0T 4QAE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?