RPTOR and RAP1B

  • Number of citations of the paper that reports this interaction (PubMedID 24337580)
  • 27

RPTOR

RAP1B

Description regulatory associated protein of MTOR complex 1 RAP1B, member of RAS oncogene family
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
Interacting Genes 22 interacting genes: CILK1 DUXAP9 EIF4EBP1 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB WIPI2 29 interacting genes: A2M ALAS1 APLP1 APP CCT7 CHGB CSAD DDAH2 FAF1 HRAS KMT2B LRIF1 PDHB PKM PRKACA RAB7B RALGDS RAPGEF1 RASSF5 RGL2 RGS2 RPTOR SDF4 SMURF2 TLE1 TP53 UNC119 ZDHHC17 ZNF135
Entrez ID 57521 5908
HPRD ID 06184 01546
Ensembl ID ENSG00000141564 ENSG00000127314
Uniprot IDs Q6DKI0 Q8N122 A0A024RB87 B7ZAY2 P61224
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62 3BRW 3CF6 4DXA 4HDO 4HDQ 4M8N 4MGI 4MGK 4MGY 4MGZ 4MH0 5KHO 6AXF 6BA6
Enriched GO Terms of Interacting Partners?
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