RPTOR and NRBF2

  • Number of citations of the paper that reports this interaction (PubMedID 28059666)
  • 17
  • Data Source:
  • BioGRID (enzymatic study)

RPTOR

NRBF2

Description regulatory associated protein of MTOR complex 1 nuclear receptor binding factor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
  • Atrial fibrillation ( 30061737)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 22001757)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mean corpuscular volume ( 27863252)
  • Mean platelet volume ( 24026423)
  • Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
  • Schizophrenia ( 28991256 30285260)
  • Triglyceride levels ( 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 22 interacting genes: CILK1 DUXAP9 EIF4EBP1 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB WIPI2 9 interacting genes: C1orf216 HNF4A IKBKG PPARA RARA RHOU RPTOR RXRA THRB
Entrez ID 57521 29982
HPRD ID 06184 11401
Ensembl ID ENSG00000141564 ENSG00000148572
Uniprot IDs Q6DKI0 Q8N122 Q96F24
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62 4ZEY
Enriched GO Terms of Interacting Partners?
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