PTK2 and PIAS1

  • Number of citations of the paper that reports this interaction (PubMedID 14500712)
  • 37
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

PTK2

PIAS1

Description protein tyrosine kinase 2 protein inhibitor of activated STAT 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Atrial fibrillation ( 30061737 29892015)
  • Diastolic blood pressure ( 30224653)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mood instability ( 31168069)
  • Nickel levels ( 26025379)
  • Response to interferon beta therapy ( 21502966)
  • Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes 112 interacting genes: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 DOK4 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PKD1 PLCG1 PPP1CB PTEN PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SH2D1A SH2D1B SHC1 SOCS1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TNS3 TP53 TRIM15 TRIO TRIP6 TSC2 VCL YES1 ZFYVE21 ZNF331 107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76
Entrez ID 5747 8554
HPRD ID 02859 16029
Ensembl ID ENSG00000169398 ENSG00000033800
Uniprot IDs Q05397 Q59GM6 Q59GN8 Q658W2 O75925 Q1XBU8
PDB IDs 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO 4NY0 4Q9S 6I8Z 1V66
Enriched GO Terms of Interacting Partners?
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