RHBG and SH2B1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RHBG	SH2B1
Description		Rh family B glycoprotein (gene/pseudogene)	SH2B adaptor protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Cytoplasmic Vesicle Membrane Anchored Component Of Plasma Membrane	Nucleus Cytosol Plasma Membrane
	Molecular Function	Ammonium Transmembrane Transporter Activity Ankyrin Binding	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Protein Binding
	Biological Process	Ammonium Transport Transepithelial Ammonium Transport Ammonium Transmembrane Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Blood Coagulation Lamellipodium Assembly Intracellular Signal Transduction Positive Regulation Of Mitotic Nuclear Division Positive Regulation Of SMAD Protein Signal Transduction Regulation Of DNA Biosynthetic Process
Pathways		Rhesus glycoproteins mediate ammonium transport.	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Initial pursuit acceleration ( 29064472) Subcutaneous adipose tissue ( 22589738) Visceral adipose tissue adjusted for BMI ( 22589738)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 19079260 19079261 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Cognitive ability ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Crohn's disease ( 28067908 21102463) Dental caries (decayed, missing and filled teeth) ( 31533690) Educational attainment ( 25201988) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hand grip strength ( 29691431) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Mean corpuscular volume ( 27863252) Obesity ( 23563607) QT interval ( 29213071) Red blood cell count ( 27863252) Waist circumference ( 25673412) Weight ( 19079260)
Interacting Genes		1 interacting genes: SH2B1	13 interacting genes: CSAD EGFR FGFR3 FRS3 GRB2 IGF1R INSR JAK2 KIAA0319 NTRK1 NTRK2 RHBG SH2B2
Entrez ID		57127	25970
HPRD ID		06152	12336
Ensembl ID		ENSG00000132677	ENSG00000178188
Uniprot IDs		Q9H310	A0A024QZ92 A0A024QZC2 A0A024QZD2 B3KNV5 B4DLN5 Q9NRF2
PDB IDs			5W3R
Enriched GO Terms of Interacting Partners?
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