MAP3K7CL and CISH

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		MAP3K7CL	CISH
Description		MAP3K7 C-terminal like	cytokine inducible SH2 containing protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cellular_component Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex
	Molecular Function	Protein Binding	Molecular_function Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process		Regulation Of Cell Growth Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Interleukin-7-mediated Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Phosphatidylinositol Phosphorylation
Pathways			Interleukin-7 signaling Neddylation Growth hormone receptor signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010) Ventricular ectopy ( 29618737)	Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
Interacting Genes		6 interacting genes: AK8 CISH GPS2 KRT31 REL TAB3	18 interacting genes: CSF2RB CSF3R EPOR ERBB2 ETV5 GHR GPX1 HSPA6 IL2RB IL3RA KIT MAP3K7CL MYD88 PRKCA PRKCB PRKCQ PRLR SMAD2
Entrez ID		56911	1154
HPRD ID		10764	03897
Ensembl ID		ENSG00000156265	ENSG00000114737
Uniprot IDs		B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077	Q9NSE2
PDB IDs
Enriched GO Terms of Interacting Partners?
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