THAP12 and TACC1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		THAP12	TACC1
Description		THAP domain containing 12	transforming acidic coiled-coil containing protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding Protein Dimerization Activity	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Signal Transduction Negative Regulation Of Cell Proliferation	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Proliferation Cerebral Cortex Development Cell Division Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity
Pathways
Drugs
Diseases
GWAS		Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433)	Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)
Interacting Genes		8 interacting genes: DDX58 DNAJC3 EIF2AK2 EIF2S1 MAPKAPK3 STK4 TACC1 TP53	15 interacting genes: AURKA AURKB BTRC HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 YEATS4
Entrez ID		5612	6867
HPRD ID		09567	10391
Ensembl ID		ENSG00000137492	ENSG00000147526
Uniprot IDs		A0A140VJQ7 O43422	E7EVI4 O75410 Q5HYH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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