CAND1 and DCUN1D5

Number of citations of the paper that reports this interaction (PubMedID 26906416)
9

Data Source:
BioGRID (pull down)

		CAND1	DCUN1D5
Description		cullin associated and neddylation dissociated 1	defective in cullin neddylation 1 domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Cell Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Cullin-RING Ubiquitin Ligase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Ubiquitin Ligase Complex Cellular_component
	Molecular Function	Protein Binding TBP-class Protein Binding	Molecular_function Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Cellular Iron Ion Homeostasis SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Neutrophil Degranulation Post-translational Protein Modification Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Biological_process Protein Neddylation Positive Regulation Of Ubiquitin-protein Transferase Activity
Pathways		Neutrophil degranulation Neddylation Iron uptake and transport	Neddylation
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Expressive vocabulary in infants ( 25226531) Hippocampal atrophy ( 19668339) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diisocyanate-induced asthma ( 25918132) Interleukin-10 levels ( 22205395) Toenail selenium levels ( 25343990) Tuberculosis ( 24057671)
Interacting Genes		16 interacting genes: CA9 CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 DCUN1D2 DCUN1D4 DCUN1D5 MTNR1A RBX1 SKP1 SRPK2 UBE2M	8 interacting genes: CAND1 CHUK CUL2 CUL3 LNX1 RCHY1 UBE2F UBE2M
Entrez ID		55832	84259
HPRD ID		06983	14520
Ensembl ID		ENSG00000111530	ENSG00000137692
Uniprot IDs		Q86VP6	A0A024R3A2 B4DP84 Q9BTE7
PDB IDs		1U6G 4A0C
Enriched GO Terms of Interacting Partners?
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