CAND1 and CA9

Number of citations of the paper that reports this interaction (PubMedID 28388044)
2

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		CAND1	CA9
Description		cullin associated and neddylation dissociated 1	carbonic anhydrase 9
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Cell Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Cullin-RING Ubiquitin Ligase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleolus Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Microvillus Membrane
	Molecular Function	Protein Binding TBP-class Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding
	Biological Process	Cellular Iron Ion Homeostasis SCF Complex Assembly Protein Ubiquitination Cell Differentiation Negative Regulation Of Catalytic Activity Neutrophil Degranulation Post-translational Protein Modification Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Morphogenesis Of An Epithelium Bicarbonate Transport Response To Testosterone Response To Drug Secretion Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways		Neutrophil degranulation Neddylation Iron uptake and transport	Regulation of gene expression by Hypoxia-inducible Factor Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Zonisamide Hydrochlorothiazide WX-G250 Ellagic Acid Sodium carbonate
Diseases
GWAS		Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Expressive vocabulary in infants ( 25226531) Hippocampal atrophy ( 19668339) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653)
Interacting Genes		16 interacting genes: CA9 CNOT3 CUL1 CUL2 CUL3 CUL4A CUL4B DCUN1D1 DCUN1D2 DCUN1D4 DCUN1D5 MTNR1A RBX1 SKP1 SRPK2 UBE2M	5 interacting genes: CAND1 CDH1 CTNNA1 CTNNB1 GLRX3
Entrez ID		55832	768
HPRD ID		06983	04417
Ensembl ID		ENSG00000111530	ENSG00000107159
Uniprot IDs		Q86VP6	A0A0S2Z3D0 Q16790
PDB IDs		1U6G 4A0C	2HKF 3IAI 5DVX 5FL4 5FL5 5FL6 6FE0 6FE1 6FE2 6G98 6G9U 6RQN 6RQQ 6RQU 6RQW
Enriched GO Terms of Interacting Partners?
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