ADAP2 and RANBP9

Number of citations of the paper that reports this interaction (PubMedID 18298663)
6

Data Source:
BioGRID (pull down)

		ADAP2	RANBP9
Description		ArfGAP with dual PH domains 2	RAN binding protein 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Envelope Plasma Membrane Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein Binding, Bridging Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Heart Development Positive Regulation Of GTPase Activity Inositol Lipid-mediated Signaling	MAPK Cascade Microtubule Nucleation Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade
Pathways			L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS		Height ( 28552196) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252)	Breast cancer ( 29059683 23535729)
Interacting Genes		9 interacting genes: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA TUBB	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		55803	10048
HPRD ID		16357	04835
Ensembl ID		ENSG00000184060	ENSG00000010017
Uniprot IDs		Q2V6Q1 Q9NPF8	A0A024QZW3 Q96S59
PDB IDs			5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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