LRIF1 and SUPT4H1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		LRIF1	SUPT4H1
Description		ligand dependent nuclear receptor interacting factor 1	SPT4 homolog, DSIF elongation factor subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Barr Body Nucleoplasm Nuclear Matrix Centriolar Satellite	Nucleus Nucleoplasm DSIF Complex
	Molecular Function	Protein Binding Retinoic Acid Receptor Binding	RNA Polymerase II Complex Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Zinc Ion Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Dosage Compensation By Inactivation Of X Chromosome	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Viral Transcription
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Intraocular pressure ( 30591961)	Mental health study participation (completed survey) ( 31263887)
Interacting Genes		130 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 CLCC1 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24	11 interacting genes: ANXA5 APP EWSR1 HTATSF1 LRIF1 LRRK2 MFHAS1 NSG2 PDLIM1 SUPT5H XRCC5
Entrez ID		55791	6827
HPRD ID		17975	16026
Ensembl ID		ENSG00000121931	ENSG00000213246
Uniprot IDs		Q5T3J3	P63272
PDB IDs			3H7H 5OIK 6GMH 6GML
Enriched GO Terms of Interacting Partners?
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