PRKAR2B and MT1H

		PRKAR2B	MT1H
Description		protein kinase cAMP-dependent type II regulatory subunit beta	metallothionein 1H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Neuronal Cell Body Dendritic Spine Dendritic Shaft Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Ciliary Base Glutamatergic Synapse	Cell Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity Protein Domain Specific Binding CAMP Binding Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Renal Water Homeostasis Fatty Acid Metabolic Process Blood Coagulation Learning Regulation Of G2/M Transition Of Mitotic Cell Cycle CGMP-mediated Signaling Activation Of Protein Kinase A Activity Intracellular Signal Transduction Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Response To Clozapine Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of CAMP-dependent Protein Kinase Activity	Cellular Zinc Ion Homeostasis Detoxification Of Copper Ion Negative Regulation Of Growth Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion
Pathways		PKA activation PKA activation in glucagon signalling DARPP-32 events Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production	Metallothioneins bind metals
Drugs		Cyclic Adenosine Monophosphate
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Bladder cancer (smoking interaction) ( 24662972) Blood urea nitrogen levels ( 31152163) Height ( 28552196) Manganese levels ( 26025379) Response to antipsychotic treatment ( 20195266)	Gambling ( 22780124)
Interacting Genes		24 interacting genes: ABCB4 AKAP1 AKAP10 AKAP11 AKAP14 AKAP4 AKAP5 AKAP7 AKAP9 CBR1 CFAP91 GNAI3 KIF5B LAMB1 LASP1 LRCH4 MT1H NBEA PAK1IP1 PRKACA RAP2B RPL30 TAF12 TFR2	3 interacting genes: PRKAR2B SERPINB5 SPINK7
Entrez ID		5577	4496
HPRD ID		01486	01128
Ensembl ID		ENSG00000005249	ENSG00000205358
Uniprot IDs		A0A024R712 B3KY43 P31323	A0A140VJP7 P80294
PDB IDs
Enriched GO Terms of Interacting Partners?
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