HIF1AN and ASB9

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		HIF1AN	ASB9
Description		hypoxia inducible factor 1 subunit alpha inhibitor	ankyrin repeat and SOCS box containing 9
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Mitochondrion Cytosol
	Molecular Function	Notch Binding Iron Ion Binding Protein Binding Zinc Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Oxygen Sensor Activity Carboxylic Acid Binding Peptidyl-histidine Dioxygenase Activity Peptidyl-asparagine 3-dioxygenase Activity Protein Homodimerization Activity Cofactor Binding NF-kappaB Binding Ankyrin Repeat Binding Hypoxia-inducible Factor-asparagine Oxygenase Activity	Protein Binding
	Biological Process	Peptidyl-histidine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Peptidyl-asparagine Hydroxylation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Notch Signaling Pathway Oxidation-reduction Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Vasculogenesis	Protein Ubiquitination Intracellular Signal Transduction Post-translational Protein Modification Positive Regulation Of Protein Catabolic Process
Pathways		Cellular response to hypoxia	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		D-tartaric acid N-(carboxycarbonyl)-D-phenylalanine
Diseases
GWAS		Body mass index ( 28892062 25673413) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303)	Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: ASB13 ASB4 ASB9 FBF1 HDAC1 HDAC2 HDAC3 HIF1A INVS NAA10 SIAH1 TP53BP2 UACA VHL	4 interacting genes: CKB HIF1AN PLCG2 UBE2D1
Entrez ID		55662	140462
HPRD ID		09426	06452
Ensembl ID		ENSG00000166135	ENSG00000102048
Uniprot IDs		Q9NWT6	A0A024RBW2 A0A024RBW7 A0A024RBZ4 Q96DX5
PDB IDs		1H2K 1H2L 1H2M 1H2N 1IZ3 1MZE 1MZF 1YCI 2CGN 2CGO 2ILM 2W0X 2WA3 2WA4 2XUM 2Y0I 2YC0 2YDE 3D8C 3KCX 3KCY 3OD4 3P3N 3P3P 4AI8 4B7E 4B7K 4BIO 4JAA 4NR1 4Z1V 4Z2W 5JWK 5JWL 5JWP 5OP6 5OP8 5OPC 6H9J 6HA6 6HC8 6HKP 6HL5 6HL6	3D9H 3ZKJ 3ZNG
Enriched GO Terms of Interacting Partners?
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