OTUD5 and NONO

Number of citations of the paper that reports this interaction (PubMedID 30508113)
2

Data Source:
BioGRID (pull down)

		OTUD5	NONO
Description		OTU deubiquitinase 5	non-POU domain containing octamer binding
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GO Annotations	Cellular Component	Cytosol	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding
	Biological Process	Protein Deubiquitination Negative Regulation Of Type I Interferon Production Response To Lipopolysaccharide Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways		Ovarian tumor domain proteases Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS
Interacting Genes		12 interacting genes: ARPC3 NEDD8 NONO PDCD5 POLR2A POLR2B POLR2C SUB1 TP53 TRAF3 UBC UBR5	42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1
Entrez ID		55593	4841
HPRD ID		06488	02098
Ensembl ID		ENSG00000068308	ENSG00000147140
Uniprot IDs		A0A024QZ09 Q96G74	A0A0S2Z4Z9 Q15233
PDB IDs		3PFY 3TMO 3TMP	3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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