PRIM1 and MRPL38

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		PRIM1	MRPL38
Description		DNA primase subunit 1	mitochondrial ribosomal protein L38
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GO Annotations	Cellular Component	Nucleoplasm Alpha DNA Polymerase:primase Complex Membrane	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Single-stranded DNA Binding DNA Primase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Asthma ( 31619474) Height ( 31562340) Mean corpuscular volume ( 27863252) Menopause (age at onset) ( 22267201 26414677) Plateletcrit ( 27863252) Red blood cell count ( 29403010)
Interacting Genes		14 interacting genes: MDC1 MRPL38 NFE2 PDE1B PRIM2 RAB5B RARG RPS26 SENP1 SLC11A2 SLC26A8 STAT6 TP53 YIF1A	5 interacting genes: CSNK2A1 DOCK8 ERG28 HSPB3 PRIM1
Entrez ID		5557	64978
HPRD ID		08899	14758
Ensembl ID		ENSG00000198056	ENSG00000204316
Uniprot IDs		P49642	Q96DV4
PDB IDs		4BPU 4BPW 4BPX 4LIK 4LIL 4MHQ 4RR2 5EXR 6R4S 6R4T 6R4U 6R5D 6R5E 6RB4	3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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