PRIM1 and YIF1A

		PRIM1	YIF1A
Description		DNA primase subunit 1	Yip1 interacting factor homolog A, membrane trafficking protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Alpha DNA Polymerase:primase Complex Membrane	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane
	Molecular Function	Single-stranded DNA Binding DNA Primase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication	ER To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Asthma ( 31619474) Height ( 31562340) Mean corpuscular volume ( 27863252) Menopause (age at onset) ( 22267201 26414677) Plateletcrit ( 27863252) Red blood cell count ( 29403010)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		14 interacting genes: MDC1 MRPL38 NFE2 PDE1B PRIM2 RAB5B RARG RPS26 SENP1 SLC11A2 SLC26A8 STAT6 TP53 YIF1A	16 interacting genes: ADAM17 CDK2AP2 GNL1 HEATR1 KAT5 KCNK5 MRPL18 PRIM1 SLC34A1 SLCO2B1 STARD10 STIP1 VKORC1 WDR74 YIPF5 ZDHHC17
Entrez ID		5557	10897
HPRD ID		08899	06755
Ensembl ID		ENSG00000198056	ENSG00000174851
Uniprot IDs		P49642	A6NGW1 A8K509 O95070
PDB IDs		4BPU 4BPW 4BPX 4LIK 4LIL 4MHQ 4RR2 5EXR 6R4S 6R4T 6R4U 6R5D 6R5E 6RB4
Enriched GO Terms of Interacting Partners?
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