SRGN and UBR4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		SRGN	UBR4
Description		serglycin	ubiquitin protein ligase E3 component n-recognin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Secretory Granule Platelet Alpha Granule Lumen Mast Cell Granule Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Postsynaptic Specialization, Intracellular Component	Nucleoplasm Centrosome Cytosol Plasma Membrane Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Calmodulin Binding Zinc Ion Binding
	Biological Process	Platelet Degranulation Granzyme-mediated Apoptotic Signaling Pathway Protein Processing Negative Regulation Of Bone Mineralization Biomineral Tissue Development Secretory Granule Organization Mast Cell Secretory Granule Organization T Cell Secretory Granule Organization Maintenance Of Protease Location In Mast Cell Secretory Granule Maintenance Of Granzyme B Location In T Cell Secretory Granule Negative Regulation Of Cytokine Secretion Modulation Of Chemical Synaptic Transmission Regulation Of Postsynapse Organization	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Ubiquitination Neutrophil Degranulation
Pathways		Platelet degranulation	Neutrophil degranulation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			HspE7 PCL-016
Diseases
GWAS		Glycemic traits (pregnancy) ( 23903356)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Composite immunoglobulin trait (IgA/IgG) ( 28628107)
Interacting Genes		13 interacting genes: ALB BAG6 CCL3 CD44 CEP70 FHL3 GZMB PF4 PSRC1 SGTA UBQLN1 UBQLN4 UBR4	10 interacting genes: CALM1 ERG MTNR1A MTNR1B PRPF40A SRGN SRPK2 UBC UBE2D2 UBE2L3
Entrez ID		5552	23352
HPRD ID		01513	10184
Ensembl ID		ENSG00000122862	ENSG00000127481
Uniprot IDs		P10124	Q5T4S7
PDB IDs
Enriched GO Terms of Interacting Partners?
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