STRBP and THAP1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		STRBP	THAP1
Description		spermatid perinuclear RNA binding protein	THAP domain containing 1
Image
GO Annotations	Cellular Component	Manchette Nucleus Cytoplasm	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Microtubule Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding
	Biological Process	Multicellular Organism Development Spermatid Development Mechanosensory Behavior	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Birth weight ( 27680694) Body mass index ( 26426971) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 31562340 31217584)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		9 interacting genes: ARNT DAB1 EIF2AK2 LRRK2 MAP4 RBFOX1 RBPMS THAP1 ZMAT4	65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		55342	55145
HPRD ID		10257	15496
Ensembl ID		ENSG00000165209	ENSG00000131931
Uniprot IDs		A0A0S2Z5K8 Q96SI9 V9HWK4	Q9NVV9
PDB IDs		2DMY	2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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