ABCF3 and THAP1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ABCF3	THAP1
Description		ATP binding cassette subfamily F member 3	THAP domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Nuclear Chromatin Fibrillar Center Nucleus Nucleoplasm PML Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding ATP Binding ATPase Activity Cadherin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding
	Biological Process	Defense Response To Virus	Negative Regulation Of Transcription By RNA Polymerase II Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Major depressive disorder ( 22472876)	Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		20 interacting genes: ACIN1 CCDC33 DLEU1 DNALI1 FBXO7 FCHSD2 HIRIP3 LAMTOR1 MDFI MOCS2 NOA1 PSME3 RBPMS SLC35E1 SPP1 TBPL1 THAP1 TOE1 TRIM14 TRIM27	65 interacting genes: ABCF3 ACOT7 AEBP2 AKAP17A AKAP9 AP2B1 APP ARL6IP4 BAG5 BMS1P1 BYSL C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 EEF1AKNMT FAM124A FAM133A FXR2 GOLGA7 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NKAPD1 NTAQ1 NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM10 RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WT1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		55324	55145
HPRD ID		12404	15496
Ensembl ID		ENSG00000161204	ENSG00000131931
Uniprot IDs		A0A0S2Z5L1 Q9NUQ8	Q9NVV9
PDB IDs			2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?
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