PPP3CB and PTK7

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		PPP3CB	PTK7
Description		protein phosphatase 3 catalytic subunit beta	protein tyrosine kinase 7 (inactive)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Calcineurin Complex Z Disc T-tubule Glutamatergic Synapse	Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Drug Binding Enzyme Binding Protein Phosphatase 2B Binding Calmodulin-dependent Protein Phosphatase Activity Protein Dimerization Activity	Protein Kinase Activity Protein Binding ATP Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity Lymphangiogenesis Protein Phosphorylation Protein Dephosphorylation Signal Transduction Wnt Signaling Pathway, Calcium Modulating Pathway Heart Development Learning Memory Dephosphorylation Calcium Ion Regulated Exocytosis T Cell Differentiation Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade Response To Cytokine Cellular Response To Drug Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Fc-epsilon Receptor Signaling Pathway T Cell Proliferation T Cell Activation T Cell Homeostasis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Synaptic Plasticity Axon Extension Regulation Of Insulin Secretion Calcineurin-mediated Signaling Regulation Of Synaptic Vesicle Endocytosis	Establishment Of Planar Polarity Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation ROBO receptors bind AKAP5
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778)
Interacting Genes		17 interacting genes: AATK CABIN1 EGFR IRAK1 IRF2 JUN LMTK2 MARCHF7 MYOZ2 MYOZ3 NFATC2 PTK7 ROR2 SLC8A1 SLC8A2 SLC8A3 SOCS3	32 interacting genes: CDC14A CLNK CTDSP2 DUPD1 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 ERBB2 ILKAP MTMR1 MTMR10 MTMR6 MTMR9 PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2
Entrez ID		5532	5754
HPRD ID		00235	03534
Ensembl ID		ENSG00000107758	ENSG00000112655
Uniprot IDs		B7Z781 P16298	Q13308
PDB IDs		4OR9 4ORA 4ORC
Enriched GO Terms of Interacting Partners?
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