MOB1A and KANK2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MOB1A	KANK2
Description		MOB kinase activator 1A	KN motif and ankyrin repeat domains 2
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Extracellular Exosome	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Hippo Signaling	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Rho Protein Signal Transduction Negative Regulation Of Programmed Cell Death Negative Regulation Of Vitamin D Receptor Signaling Pathway Kidney Epithelium Development Glomerular Visceral Epithelial Cell Migration Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Cholesterol, total ( 26780889) Coronary artery disease ( 29212778) HDL cholesterol ( 23505323) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 31959993) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		13 interacting genes: APP CCDC85B CMTM3 FAM118A FAM9B KANK2 KXD1 MST1 PJA2 PTPN5 SEPTIN3 STRN3 TDO2	23 interacting genes: ABI3 CCDC33 CEP70 CSNK2A1 DYNLL1 EIF4E FHL2 GOLGA2 GPSM1 IHO1 LMO1 LMO2 LMO4 MAGEB4 MOB1A NCOA1 NOS3 PSEN1 SRPK2 STAC TLE5 TXLNA VPS52
Entrez ID		55233	25959
HPRD ID		14727	12463
Ensembl ID		ENSG00000114978	ENSG00000197256
Uniprot IDs		Q9H8S9	Q63ZY3
PDB IDs		1PI1 4J1V 4JIZ 5BRK 5BRM 5TWF 5TWG 5TWH 5XQZ 6MCP 6MCQ	4HBD 5YBV
Enriched GO Terms of Interacting Partners?
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