ZNF512B and KDM3B

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)

		ZNF512B	KDM3B
Description		zinc finger protein 512B	lysine demethylase 3B
Image
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Transcription Regulatory Region Sequence-specific DNA Binding Antioxidant Activity Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Metal Ion Binding Dioxygenase Activity
	Biological Process		Regulation Of Transcription, DNA-templated Histone H3-K9 Demethylation Oxidation-reduction Process Response To Cisplatin Cellular Oxidant Detoxification
Pathways			HDMs demethylate histones
Drugs
Diseases
GWAS		Birth weight ( 31043758) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321) HIV-1 susceptibility ( 25786224) Menarche (age at onset) ( 21102462 25231870) Response to radiotherapy in prostate cancer (toxicity, urinary frequency) ( 27515689) Schizophrenia ( 25056061)
Interacting Genes		60 interacting genes: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2	6 interacting genes: CREBBP H3-4 RNF41 SPAG8 UBC ZNF512B
Entrez ID		57473	51780
HPRD ID		13840	11055
Ensembl ID		ENSG00000196700	ENSG00000120733
Uniprot IDs		Q96KM6	Q7LBC6
PDB IDs		2GQJ	4C8D
Enriched GO Terms of Interacting Partners?
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