ARHGAP17 and FNBP1

Number of citations of the paper that reports this interaction (PubMedID 11431473)
37

Data Source:
HPRD (in vitro)

		ARHGAP17	FNBP1
Description		Rho GTPase activating protein 17	formin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Nucleoplasm Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding Rac GTPase Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Signal Transduction Calcium Ion Regulated Exocytosis Regulation Of Actin Cytoskeleton Organization Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Membrane Organization
Pathways		Rho GTPase cycle	Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688)
Interacting Genes		16 interacting genes: ABL1 APP BTK CDC42 CRK CTTN DNMBP FNBP1 GRB2 LCK PACSIN1 PIK3R1 RAC1 SH3GLB1 SRC TRIP10	12 interacting genes: AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL
Entrez ID		55114	23048
HPRD ID		12207	10446
Ensembl ID		ENSG00000140750	ENSG00000187239
Uniprot IDs		Q68EM7	B7ZL13 B7ZL14 Q96RU3
PDB IDs			2EFL
Enriched GO Terms of Interacting Partners?
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