FNBP1 and SNX2

Number of citations of the paper that reports this interaction (PubMedID 11438682)
21

Data Source:
HPRD (in vivo, two hybrid)

		FNBP1	SNX2
Description		formin binding protein 1	sorting nexin 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle	Cytoplasm Lysosome Endosome Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Endocytosis Membrane Organization	Intracellular Protein Transport Endocytosis Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Lamellipodium Morphogenesis
Pathways		Clathrin-mediated endocytosis	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688)	Event free survival in diffuse large B-cell lymphoma treated with immunochemotherapy ( 26460308)
Interacting Genes		12 interacting genes: AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	20 interacting genes: ACVR1B ACVR2B C1orf122 CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET NFYC PAK6 PDGFRA PDGFRB SNX1 SNX4 SNX5 SNX6 ZNF202
Entrez ID		23048	6643
HPRD ID		10446	09332
Ensembl ID		ENSG00000187239	ENSG00000205302
Uniprot IDs		B7ZL13 B7ZL14 Q96RU3	O60749
PDB IDs		2EFL
Enriched GO Terms of Interacting Partners?
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